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🫀 LDL Cholesterol (Friedewald)

Calculate LDL cholesterol from a lipid panel with the Friedewald equation.

LDL Cholesterol (Friedewald)

Total cholesterol (mg/dL)
HDL cholesterol (mg/dL)
Triglycerides (mg/dL)

When to use

Estimate LDL when a direct measurement is unavailable.

How it works

LDL = TC − HDL − TG/5 (mg/dL); invalid at triglycerides ≥ 400 mg/dL.

Key points

  • Underestimates LDL at low LDL or high triglycerides.
  • Use direct LDL or Martin-Hopkins when more accuracy is needed.
  • Requires a fasting sample for best accuracy.

References

Decision support for licensed clinicians only; not a substitute for clinical judgement, diagnosis or local protocols.

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